A Daily Foundation for COPD Management: Spiriva HandiHaler (tiotropium bromide) is a prescription inhalation powder indicated for the long-term, once-daily maintenance treatment of bronchospasm associated with COPD, including chronic bronchitis and emphysema, and to help reduce COPD exacerbations. It is not intended for sudden symptom relief.

Keeping Airways Open Through the Day: Tiotropium is a long-acting muscarinic antagonist (LAMA) that works by blocking M3 receptors in the smooth muscle of the airways, which helps relax and keep them open. Because its effects last a full 24 hours, a single daily dose is designed to provide consistent bronchodilation around the clock.

One Capsule, Delivered Through the HandiHaler Device: Each dose involves placing a Spiriva capsule into the HandiHaler device and inhaling its contents twice — never swallowing the capsule, since it only works when inhaled directly into the lungs. Dosing is limited to two inhalations from one capsule, once daily, with no more than one dose in any 24-hour period.

A Foundational LAMA in COPD Therapy: Tiotropium was one of the first long-acting muscarinic antagonists approved for COPD and remains widely used today, with an extensive body of clinical evidence supporting its role in reducing exacerbations and improving lung function in patients with chronic bronchitis and emphysema.

Supporting Steadier Breathing, Long Term: COPD tends to progress gradually, making consistent daily maintenance therapy especially important. Used as directed alongside your doctor's broader treatment plan, Spiriva HandiHaler is designed to help you breathe more steadily throughout your day.

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