One Medication, Multiple Protective Roles: Farxiga (dapagliflozin) is a prescription medication approved for type 2 diabetes, heart failure (across the full range of ejection fraction), and chronic kidney disease. It's also indicated to reduce the risk of heart failure hospitalization in adults with type 2 diabetes and cardiovascular disease or multiple cardiovascular risk factors — reflecting how closely diabetes, heart, and kidney health are connected.

Reducing Glucose the Kidney's Way: Farxiga is an SGLT2 inhibitor that works by blocking glucose reabsorption in the kidneys, causing excess sugar to be eliminated through urine instead of returning to the bloodstream. This same mechanism also reduces sodium reabsorption, which is thought to ease the workload on the heart by lowering blood pressure inside blood vessels and reducing strain on the kidneys over time.

Once-Daily Dosing Tailored to Your Condition: For type 2 diabetes, the typical starting dose is 5 mg once daily, which may be increased to 10 mg for additional blood sugar control. For heart failure, chronic kidney disease, and cardiovascular risk reduction, the standard dose is 10 mg once daily. Farxiga is not recommended for glycemic control in patients with significantly reduced kidney function, since its glucose-lowering effect depends on kidney filtration.

Backed by Major Outcomes Research: Dapagliflozin has been studied in large-scale clinical trials across diabetes, heart failure, and chronic kidney disease populations, helping establish reductions in cardiovascular death, heart failure hospitalization, and kidney disease progression — evidence that has shaped how it's used across multiple specialties.

A Broader Strategy for Long-Term Health: Type 2 diabetes rarely affects blood sugar alone — it's closely tied to heart and kidney health over time. With guidance from your healthcare provider, Farxiga can be part of a plan that addresses several of these connected risks together.

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